Twenty Recent Publications (of ~200 total publications)
- Abonia JP, Friend DS, Austen WG Jr, Moore FD Jr, Carroll MC, Chan R, Afnan J, Humbles A, Gerard C, Knight P, Kanaoka Y, Yasuda S, Morokawa N, Austen KF, Stevens RL, Gurish MF. Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle. J Immunol. 2005;174:7285-91. (view publication)
- Thakurdas SM, Melicoff E, Sansores‑Garcia L, Moreira DC, Petrova Y, Stevens RL, Adachi R. The mast cell-restricted tryptase mMCP‑6 has a critical immunoprotective role in bacteria infections. J Biol Chem. 2007;282:20809-15. (view publication)
- McNeil HP, Shin K, Campbell IK, Wicks IP, Adachi R, Lee DM, Stevens RL. The mouse mast cell-restricted tetramer-forming tryptases mMCP‑6 and mMCP‑7 are critical mediators in inflammatory arthritis. Arthritis Rheum. 2008;58:2338-46. (view publication)
- Shin K, Nigrovic PA, Crish J, Boilard E, McNeil HP, Larabee K, Adachi R, Gurish MF, Gobezie R, Stevens RL, Lee DM. Mast cells contribute to autoimmune inflammatory arthritis via their tryptase•heparin complexes. J Immunol. 2009;182:647-56. (view publication)
- Sun J, Zhang J, Lindholdt J, Sukhova GA, Liu J, He A, Åbrink M, Gunnar Pejler, Stevens RL, Thompson RW, Ennis TL, Gurish MF, Libby P, and Shi G-P. Critical role for mast cell-restricted chymases in formation of abdominal aortic aneurysms in mice and humans. Circulation 2009;120:973-82. (view publication)
- Kaieda S, Nigrovic PA, Seki K, Lee RT, Stevens RL, Lee DM. Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1). J Biol Chem. 2010;285:21478-86. (view publication)
- Younan G, Suber F, Xing W, Shi T, Kunori Y, Abrink M, Pejler G, Schlenner S, Rodewald HR, Moore FD Jr, Stevens RL, Adachi, R, Austen KF, Gurish MF. The inflammatory response following an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5. J Immunol. 2010;185:7681-90. (view publication)
- Hamilton MJ, Sinnamon MS, Lyng GD, Glickman JN, Wang X, Xing W, Krilis SA, Blumberg RS, Adachi R, Lee DM, Stevens RL. Essential role for mast cell tryptase in experimental colitis in mice. Proc Natl Acad Sci USA 2011;108:290-95. (view publication)
- Zhang J, Sun J, Lindholt JS, Sukhova GK, Sinnamon M, Stevens RL, Adachi R, Libby P, Thompson RW, Shi G-P. Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation. Cir Res. 2011;108:1316-27. (view publication)
- Prieto-García A, Zheng D, Adachi R, Xing W, Lane WS, Chung K, Anderson P, Hansbro PM, Castells M, Stevens RL. Mast cell restricted mouse and human tryptase•heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen. J Biol Chem. 2012;287:7834-44. (view publication)
- Adachi R, Krilis SA, Nigrovic PA, Hamilton MJ, Chung K, Thakurdas SM, Boyce JA, Anderson P, Stevens RL. Ras guanine nucleotide releasing protein-4 involvement in experimental arthritis and colitis. J. Biol Chem. 2012;287:20047-55. (view publication)
- Beckett EL*, Stevens RL*, Jarnicki AG, Kim RY, Hanish I, Hansbro NG, Deane A, Keely S, Horvat JC, Yang M, Oliver BG, van Rooijen N, Inman MD, Stampfli MR, Adachi R, Soberman RJ, Hamadi S, Wark EP, Foster PS, Hansbro PM. A short-term model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase. J Allergy Clin Immunol. 2013; 131:752-62. (* joint first authors) (view publication)
- Magarinos NJ, Bryant KJ, Fosang AJ, Adachi RA, Stevens RL, McNeil HP. Mast cell-restricted, tetramer-forming tryptases induce aggrecanolysis in articular cartilage by activating matrix metalloproteinase-3 and -13 zymogens. J Immunol. 2013;191:1404-12. (view publication)
- Bankova LG, Lezcano C, Pejler G, Stevens RL, Murphy GF, Austen KF, Gurish MF. The chymase mouse mast cell protease 4 mediates epidermal injury by causing loss of the tight junction protein claudin-4. J Immunol. 2014;192:2812-20. (view publication)
- Prieto-García A, Mariana C. Castells MC, Hansbro PM, Stevens RL.Mast Cell-restricted tetramer-forming tryptases and their beneficial roles in hemostasis and blood coagulation. Immunol Allergy Clin NA, 2014;34:263-81. (view publication)
- Hansbro PM*, Hamilton MJ*, Fricker M, Gellatly SL, Jarnicki AG, Zheng D, Frei SM, Wong GW, Hamadi S, Zhou S, Foster PA, Krilis SA, Stevens RL. Importance of mast cell Prss31/transmembrane tryptase/tryptase‑γ in lung function and experimental chronic obstructive pulmonary disease and colitis. J Biol Chem. 2014;289:18214-27. (*joint first authors) (view publication)
- Wong GW, Zhuo L, Kimata K, Lam BK, Satoh N, Stevens RL. Ancient origin of mast cells. Biochem Biophys Res Comm. 2014;451:314-18.(view publication)
- Douaiher J, Succar J, Lancerotto L, Gurish MF, Orgill DP, Hamilton MJ, Krilis SA, Stevens RL. Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing. Adv Immunol. 2014;122:211-251. (view publication)
- Kono M, Yasuda S, Stevens RL, Koide H, Kurita T, Shimizu Y, Kanetsuka Y, Oku K, Bohgaki T, Amengual O, Horita T, Shimizu T, Majima T, Koike T, Atsumi T. RasGRP4 is aberrantly expressed in the fibroblast-like synoviocytes of patients with rheumatoid arthritis and controls their proliferation. Arth. Rheum., in press (view publication)
- Hamilton MJ, Frei SM, Stevens RL. The multi-faceted mast cell in inflammatory bowel disease. Inflam Bowel Dis.2014;20:2364-78.(view publication)
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